치료(Treatment)

영문

1. Female aged 19 to 59 years have a complaint of cold hypersensitivity on hands and feet 
2. Subject must include at least one or more of the following symptoms below: 
  • Subject has the symptoms of cold hands and feet in normal temperature which most individuals feel no cold 
  • Subject has the symptoms of severe cold hands and feet in colder than normal temperature exposure 
  • Even subject is on the return to a warmer environment, the symptoms of cold hands and feet is not completely 
disappeared 
3.  When subject's VAS(Visual Analogue Scale) of  cold hypersensitivity on feet VAS) is 4  or more
4.  When subject's both upper arms exposure to room temperature (24℃±2), the thermal deviation between the foot (acupuncture point, LR3) with the thigh(acupuncture point, S32)  may be higher than 2℃
5.  Ability to comply with all study-related procedures, medications, and evaluations 
6.  Ability to give informed consent

영문

- Patients who are admission to calcium antagonists and beta-blockers as a treatment of cold hypersensitivity on hands 
and feet 
 - Patients who are having one or more finger gangrene or ulceration 
 - Patients who are diagnosed by hyperthyroidism or currently medicated to thyroid drugs 
 - Patients who are diagnosed by Autoimmune disease or having a positive antinuclear antibody(ANA) test 
 - Patients who are diagnosed by Carpal Tunnel Syndrome or having a positive Tinel's sign and Phalen's tests 
 - Patients who are diagnosed with Cervical disc herniation 
 - Patients who are diagnosed with diabetes 
 - Drug that may affect to the cold hypersensitivity on hands and feet(ex. anticoagulants) 
 - Moderate level of liver dysfunction(each of AST, ALT greater than 100 IU/L) or kidney dysfunction patient(creatine 2.0mg/dL) 
 - Due to the behaviour disorder or depression or anxiety neurosis or schizophrenia or serious mental illness, do not cooperate with treatment and follow up 
 - Diagnosed with moderate anemia and hematologic disorders 
(adult non-pregnant women hemoglobin level less than 7g/dL, hematocrit level less than 26%, white blood cell level greater than 11,000/mm3) 
 - Systolic blood pressure 180mmHg or diastolic blood pressure is greater than 100 mmHg based on average value of at least 2 measurements 
 - Suspected arrhythmia that showed up on electrocardiogram(ECG) or diagnosed by heart disease, such as, ischemic heart disease 
 - Alcohol or drug abuse 
 - Female patients who are pregnant (positive urin - human chorionic gonadotropin) or lactating or have the chances of pregnancy 
 - Diagnosed with malignant tumors 
 - Participated in other clinical trials 
 - Refused to participate in this trial 
 - Able to understand and speak Korean 
 - Patients who are judged to be inappropriate for the clinical study by the researchers